GeneExplorer

Conventional Thermal Cycler GeneExplorer is a qualitative gene amplification instrument newly developed by Bioer Technology. This series of products breaks the traditional design concept of Bioer company, combines the characteristics of foreign advanced temperature control technology, introduces the semiconductor ceramic temperature control cold film customized by Japan Ferrotec, and cooperates with Bioer to accumulate 17 years of manufacturing experience, aiming to produce It is a simpler and more cost-effective gene amplification instrument.

ThermoCell

New generation of dry bath is a multifunctional and multipurpose product with advanced microcomputer control and thermoelectric refrigeration technology. Host machine can be configured with many modules, which is cost-effective. It can be widely used in the preservation of samples, preservation and reaction of various enzymes, denaturation of nucleic acids and proteins, PCR reaction, denaturation of electrophoresis and coagulation of serum.

GenePure Pro 32

GenePure Pro is a new generation of automatic nucleic acid purification system with cutting-edge technology and family-style appearance developed by Bioer. It adopts Magnetic Bead separation technology and uses 96-well deep well plate as test carrier to realize automatic high-throughput and high-purity extraction and purification of DNA/RNA. It can deal with various samples including blood, tissue, andvarious cells. This system has a friendly-user interface .

GenePure Pro 96

GenePure Pro 96 can achieve the automatic nucleic acid purification of samples such as whole blood, cells, tissue etc. which greatly save user’s time and strength the efficiency. It has characteristics of small dimension, light weight and low noise. The embedded operation system can do real-time controlling with large crystal screen panel. With the transparent working cavity, users can easily see the working condition of experiment, which ensure the safety and stability of the experiment. The equipment is also equipped with various safety features such as the door-opening protection, super limit position protection and alarm, all of these supplies the experience of safety and stability.

LineGene9600

Real-Time PCR LineGene 9600 Plus adopts Ferrotec specially-made Peltier, advanced fiber optic technology, new global wide-range power supply, the unique patented block dissipation technology and bottom detection mode, which provides better heating/cooling rate, temperature accuracy, uniformity and stability. Line-Gene 9600 Plus has up to 96 sample capacity and fast speed of dual-color scanning, and the design of 5 channel detection also covers the whole fluorescence detection wavelength.Newly-designed automatic hot-lid without manual operation ensures constant pressure for various tube heights. This auto hot-lid mode could be easily integrated into various automatic systems. Its Windows tablet computer and new touch screen brings excellent operating experience.Newly-improved Line-Gene 9600 Plus Real-Time PCR detection system can satisfy various clients’ requirement either for research or clinical use.

QuantGene 9600

Real-Time PCR Based on the consistent superior quality of LineGene family, QuantGene 9600 has adopted mature thermoelectric refrigeration technology, brand-new light source and light path design. The unique constant-current power and 6-zone independent temperature control method ensure more rapid, correct and stable fluorescence quantitative analysis of the product, while maintaining its excellent performance in low energy consumption.

CLARIOstar Plus

Most flexible Plate Reader for Assay Development The CLARIOstar® Plus is our most flexible multi-mode plate reader. It comes equipped with our patented LVF MonochromatorsTM, filters, and spectrometer. Flexibility combined with the best sensitivity of its class, and our newly developed Enhanced Dynamic Range technology, make it the ideal reader for assay development. The CLARIOstar Plus is a multi-mode microplate reader with advanced LVF MonochromatorsTM, highly sensitive filters, and an ultra-fast UV/vis spectrometer. The Enhanced Dynamic Range and automatic focus technologies make manual settings superfluous and detection optimisation easier than ever. Atmospheric Control Unit, temperature incubation, multiple shaking, well scan and reagent injectors make the CLARIOstar Plus the ideal platform for any live cell-based assay. FEATURES ▪ Innovative monochromators for increased sensitivity ▪ Fully-flexible wavelengths and bandwidths ▪ Spectral scanning in ABS, FI and LUM ▪ Largest dynamic range with no manual intervention ▪ Rapid full-plate autofocus ▪ Dedicated features for live cell-based assays ▪ Ultra-fast data sampling (100 measurements/second) ▪ Dedicated laser for Alpha Technology

Omega Series

Upgradeable single and multi-mode microplate reader series By focusing on the needs of the scientific community BMG LABTECH created the Omega Plate Reader series with four multi-mode microplate readers equipped with different detection modes. Choose the right microplate reader for your research. Upgradeable plate readers The Omega Plate Reader Series offer true flexibility to provide you with the perfect reader to fulfil your requirements: from an absorbance-only SPECTROstar or luminescence-only LUMIstar to a fully-equipped POLARstar Omega with up to seven detection modes. Your chosen instrument can also be upgraded at any time if you need more features or additional detection modes.

PHERAstar FSX

Powerful and most sensitive HTS plate reader The PHERAstar® FSX is our most sensitive multi-mode reader for high-throughput screening, combining this sensitivity with fast read times. Thanks to the unique Optic Module system, Simultaneous Dual Emission, UV/vis spectrometer, and dedicated AlphaScreen® and TRF lasers, the PHERAstar FSX will perform your assay with ease and speed, even in 3456-well microplates. No longer worry about installing filters and dichroics: the PHERAstar FSX comes with easy-to-handle, assay-optimized Optic Modules which contain all application-specific filters, mirrors, dichroics and/or polarizers, and are automatically recognized by the plate reader. In addition, the PHERAstar FSX is equipped with four matched and assay-optimized photomultiplier tubes (PMTs) which are automatically selected for the relevant detection mode. You can also measure assays with two emission wavelengths at the same time thanks to the Simultaneous Dual Emission. For HTS automation purposes, the PHERAstar FSX offers improved robotic integration capabilities and multi-user control. FEATURES ▪ The most sensitive reader in fluorescence intensity and polarization ▪ The only plate reader with 5 assay-dedicated detectors ▪ Simultaneous Dual Emission, including for Alpha Technology ▪ 9 decades luminescence dynamic range ▪ Dedicated AlphaScreen®/ AlphaLISA®/ AlphaPlexTM laser ▪ New generation TRF-laser ▪ Top and bottom focal height adjustment ▪ High-precision injectors with simultaneous reagent injection and detection ▪ High-speed absorbance measurements

SPECTROstar Nano

Absorbance plate reader with cuvette port BMG LABTECH’s innovative absorbance microplate reader has the flexibility to perform assays quickly and easily in both microplates or via the built-in cuvette port. This spectrometer-based absorbance microplate reader captures a full UV/visible spectrum in less than 1 sec/well. Its speed, simple push button operation, and capacity to store individual assay protocols make the SPECTROstar® Nano the leading microplate reader for absorbance measurements. The SPECTROstar Nano is equipped with BMG LABTECH’s ultra-fast UV/vis spectrometer, which allows users to measure full-spectrum absorbance (220 –1000 nm) in less than 1 second per well. It is the ideal instrument to read all absorbance assays in a microplate or cuvette – with many common assay protocols predefined and available at the click of the mouse. FEATURES ▪ High-speed absorbance measurements ▪ Measurements in up to 1536-well plates ▪ Integrated cuvette port ▪ LVis Plate compatibility ▪ Incubation up to 45 °C ▪ Multiple shaking options ▪ Well scanning with up to 900 data points per well

VANTAstar

Flexible microplate reader with simplified workflows The new VANTAstarTM is the latest addition to our family. This compact multi-mode microplate reader was conceived for ease-of-use and flexibility and ensures effortless detection setup for a simplified data generation. Equipped with our patented dual LVF MonochromatorsTM system, filters, UV/vis spectrometer, and Enhanced Dynamic Range technology, it can cover a wide range of applications in basic research and life science. VANTAstar The VANTAstar is an upgradable multi-mode microplate reader compatible with all plate formats up to 384 wells. The Enhanced Dynamic Range (EDR) technology, a fast full-plate auto-focus and luminescence cross-talk reduction make assay detection easier than ever and manual optimisation superfluous. With its Atmospheric Control Unit for gas control, temperature incubation, multiple shaking options, well scan and reagent injectors with heater and stirrer, the VANTAstar supports all live cell-based assays. . Features ▪ LVF Monochromators for wavelength flexibility and performance ▪ Automatic sensitivity adjustment with EDR ▪ Rapid full-plate auto-focus ▪ Optimised luminescence detection with automatic cross-talk reduction ▪ Spectral scanning in absorbance, fluorescence and luminescence ▪ Dedicated features for live cell-based assays ▪ Full top/bottom detection capability with automatic switch ▪ Reduced footprint ▪ Easily integrated into automated systems

MultiSUB Choice

The MultiSUB Choice offers a wide degree of versatility. Three tray options are available; 15x 7cm, 15 x 10cm and 15 x 15cm – allowing the choice of one, two or all three gel length options at the time of purchase. Further purchases of additional accessories are no longer required. Maximising comb and tray options allow up to 210 samples to be resolved per gel. The 15cm total run length allows restriction fragment or other close MW sample bands to be easily separated and identified. Speed loading is accomplished using 10, 14, 16, or 18 sample multi-channel pipette compatible combs. Fabricated MultiSUB choice stretch units are available with optional 15 x 20cm and 15 x 25cm gel trays and four 28-sample combs for those researchers wanting to perform higher resolution separation of more samples over a longer distance. MultiSUB Choice Trio includes all 3 tray sizes for optimum versatility and value. MultiSUB Choice ST A ‘stretched’ version of the MSCHOICE, this system is perfect for extended high-resolution separations of samples from 96-well microplates and blokcs, using its 15 x 20cm and 15 x 25cm gel trays and four 28-sample multichannel compatible combs. It may also be used for routine preparatory techniques. Variations MultiSUB Choice ▪ 15 x 7cm ▪ 15 x 10cm ▪ 15 x 15cm MultiSUB Choice Stretched ▪ 15 x 20cm ▪ 15 x 25cm

MultiSUB Maxi

The MultiSUB Maxi is primarily designed for resolution of high numbers of samples, such as from Cloning or PCR. The MultiSUB Maxi allows ultra high-resolution separations over extended runs. Tray sizes correspond to standard blotter sizes. It also allows easy sample transfer onto a membrane for further analysis. Four gel tray sizes are available; 20 x 10cm, 20 x 15cm, 20 x 20cm and 20 x 25cm. Multichannel pipette compatible combs of up to 40 samples facilitate speed loading of up to 440 samples per gel. 50 sample combs allow maximum sample capacity of 550 samples per gel. Casting dams allow gels to be rapidly cast externally while the MultiSUB Maxi unit is in use for gel running. Variation ▪ 20 x 10cm ▪ 20 x 15cm ▪ 20 x 20cm ▪ 20x 25cm

MultiSUB Midi

With gel tray options of 10 x 7cm and 10 x 10cm, the MultiSUB Midi has been designed for routine horizontal gel electrophoresis. Extending only the width of this unit allows more samples to be resolved per gel than the MultiSUB Mini, without a significant increase in buffer or gel volumes. A maximum of 100 samples per gel can be resolved, making this unit ideal for those routinely checking medium numbers of samples over short to medium gel run lengths. Loading guides allow easy well identification and sample loading. Scoops are also available as an option to allow safe transfer of gels. Variations ▪ 10 x 7cm ▪ 10 x 10cm

MultiSub Mini

The MultiSUB Mini is the smallest unit in the range, designed for low to medium numbers of samples. The small gel size maximises run economy but does not compromise versatility as two tray options are available – 7 x 7cm and 7 x 10cm – and combs ranging from preparative up to 16 samples. Simply by altering the gel tray or comb, this compact unit is capable of resolving up to 64 different samples, prepping 1ml of sample or separating sample bands over a distance of 9cm. Buffer saver blocks physically reduce the volume of a gel chamber and buffer requirements, therefore saving cost. Variations ▪ 7 x 7cm ▪ 7 x 10cm

DeNovix

DS-11 Microvolume Spectrophotometer

UV-Vis Microvolume and Cuvette Spectrophotometer, Flourescence The DeNovix team developed a combination of opto-mechanical components and software algorithms that optimize results for every sample. Micron-level pathlength control and immediate absorbance feedback deliver the most sensitive and accurate microvolume measurements. DeNovix Spectrophotometers quantify nucleic acids and protein using only 0.5 – 1.0 μL of sample. Just pipette and measure – no dilutions necessary. Instant on-screen results includes concentration, a full spectrum output, purity ratios and SmartQCTM contamination alerts. DeNovix SmartPath® Technology ensures instruments are calibrated for life with no drift or service downtime. Bridge Testing® eliminates broken samples columns and ensures exceptional results, even for 1 μL protein samples. Use standard quartz or disposable cuvettes for up to 10 mm pathlength absorbance measurements (190-840 nm). Cuvette applications include nucleic acids, proteins, colorimetric assays, OD600 and custom standard curves. Systems include a cuvette block heater for Kinetics studies from 37-45°C. Improve the detection limit of dsDNA 1000X by using fluorescent techniques. Specialized assay chemistries enable highly sensitive and molecule specific quantification, e.g. measuring only dsDNA in samples containing RNA and other contaminants. With four user-selectable LED excitations sources, DeNovix fluorometers are compatible with most commonly available fluorescence kits including DeNovix RNA, DeNovix dsDNA and Qubit® Fluorescence Assays. Key Features ▪ Quantify DNA, RNA and protein in less than 3 sec ▪ Widest dynamic range and lowest detection limit 0.75 – 37500 ng/μL dsDNA ▪ No routine maintenance or recalibration required ▪ Full spectrum UV-Vis analysis using 0.5 – 1.0 μL of sample

IKA

Vortex 3

Vortex shaker suitable for short-time operation (touch function), activated by pressing shaker attachment or continuous operation. ▪ Wide speed range, infinitely adjustable ▪ Different applications thanks to 3 interchangeable attachments and 7 inserts (e.g. Eppendorf tubes, microtiter plates, Erlenmeyer flasks 250 ml etc.), please order separately ▪ Attachments securely click onto appliance in any position ▪ Special strap (VG 3.36, page 51) ensures easy handling of round/Erlenmeyer flasks ▪ Sturdy metal zinc die cast casing ▪ Compact design ▪ Short-time operation activated by pressing attachment (touch function) ▪ Stable at high speeds thanks to special feet (silicon base with ultra high vibration damping) ▪ Eccentric with ball bearings ▪ Suitable for continuous operation with low self heating thanks to self ventilation of motor Shaking movement: orbital Orbital diameter: 4 mm Infinitely adjustable speed range: 500 – 2.500 rpm

Julabo THE TEMPERATURE CONTROL COMPANY

CORIO laboratory circulators

Circulators are an important part of daily work in many laboratories of research institutions and industrial companies worldwide. The JULABO CORIO circulators have been developed with pioneering technologies for these laboratories and are manufactured to the highest quality standards in Germany. Best price-performance ratio The CORIO series offers the best price-performance ratio in the basic range of circulator technology. Equipped with all essential core functions, the CORIO circulators are optimized for simple, daily routine work. Clever operation The simple and modern design of the CORIO circulators is designed for easy and time-saving operation and provides quick access to all relevant functions. A bright display means that data are always easy to read. Internal and external temperature control CORIO C and CD models are the perfect circulators for precise, internal standard temperature applications. Refrigerated circulators in the CORIO CP series expand the range of possible applications with a temperature range from -50 °C to +200 °C. Strong pump performance makes the CP models perfect for use in the simple temperature control of external applications Flexible all-rounder Universal bath attachment clamps for custom containers, bath tanks in various sizes and designs as well as powerful cooling machines make the CORIO a flexible all-rounder in everyday laboratory work. With a wide selection of accessories, all CORIO devices can be adapted to customer-specific applications in a modular and individual way. Products CORIO CD refrigerated / heating circulators The new generation of laboratory circulators for routine work and standard tasks Refrigerated / heating circulators of the CORIO series distinguish themselves with a great price-to- performance ratio. They are ideal for all standard tasks and routine work in laboratories and industry. CORIO CP refrigerated / heating circulators with an enhanced pump performance and a temperature range up to +200 °C Refrigerated circulators from the CORIO CP range are suitable for applications with a temperature range up to +200°C. The enhanced pump performance ensures they are suitable for easy temperature control tasks in combination with external applications. CORIO C heating immersion circulators The new generation of laboratory circulators The CORIO C immersion circulator is the basic model of the CORIO circulator portfolio. The bath attachment clamp is included in delivery and facilitates mounting of the circulator on any bath tank up to 30 liters. CORIO CD heating immersion circulators The new generation of laboratory circulators In addition to the advantages of the CORIO C circulator, the CORIO CD immersion circulator can be equipped with an optional pump set for temperature control of external applications. CORIO CP heating immersion circulators Laboratory circulators with an expanded working temperature range up to +200 °C In addition to the advantages of the CORIO C circulator, the CORIO CD and CP immersion circulator can be equipped with an optional pump set for temperature control of external applications. CORIO C Open heating bath circulators with transparent bath tanks Laboratory circulators for internal temperature application at working temperatures from +20 to +100°C The open heating bath circulators of the new CORIO series feature high-quality transparent bath tanks. CORIO C with stainless steel bath tanks Laboratory circulators for internal temperature application at working temperatures from +20 to +100°C The open heating bath circulators of the new CORIO series feature high-quality bath tanks made of stainless steel. CORIO CD with transparent open bath for internal and external applications at working temperatures from +20 °C to +100 °C The open heating bath circulators of the new CORIO series feature high-quality transparent bath tanks and pump connections. CORIO CD heating circulators with stainless steel open bath for internal and external applications at workingtemperatures up to +150 °C The open heating bath circulators of the new CORIO series feature high-quality bath tanks made of stainless steel. CORIO CD heating circulators for internal and external temperature tasks with insulated stainless steel bath tanks and working temperatures from +20 °C to +150 °C for internal and external temperature applications with stainless steel bath tanks and working temperatures from +20 °C to +150 °C

Julabo THE TEMPERATURE CONTROL COMPANY

DYNEO laboratory circulators

Circulators are an important part of daily work in many laboratories of research institutions and industrial companies worldwide. With the DYNEO series, we offer our customers the ideal instruments for internal and external applications in a wide working temperature range of -50 °C to +200 °C. Thanks to the proven JULABO premium quality, all models meet the highest standards in terms of precision, reliability, and functionality. Perfect for industry and laboratories Whether for demanding temperature control requirements in basic research, in material testing or in technical systems – the DYNEO refrigerated circulators offer functional solutions for every requirement and budget. Modern control The DYNEO series offers a simple, modern control option with the unique rotary knob. The entire menu, all functions and settings are controlled directly via the central rotary knob on the front of the circulator. Individual customization With a wide selection of accessories, all DYNEO instruments can be adapted to customer-specific applications in a modular and individual way. Modern interfaces and an integrated programmer complete the intelligent design of the DYNEO models. Flexible use Refrigerated circulators of the DYNEO generation are robust, reliable, and efficient. Their wide working temperature range means that the instruments can be flexibly used for internal and external applications in laboratories and technical facilities worldwide. Products DYNEO DD refrigerated / heating circulators New temperature control technology for demanding applications Refrigerated circulators of the DYNEO series distinguish themselves with a great price-performance ratio. The instruments offer high heating/cooling capacities for short heat-up and cool-down times. The refrigerated circulators work precisely and reliably even at higher ambient temperatures up to +40 °C. Either in basic research, in material testing or in technical systems – the DYNEO refrigerated circulators offer functional solutions for every requirement and budget.

Julabo THE TEMPERATURE CONTROL COMPANY

MAGIO laboratory circulators

With the new MAGIO series, JULABO is expanding its product portfolio of high-end bridge mounted circulators, refrigerated and heating circulators – naturally all in the usual premium quality. The circulators operate in a working temperature range from -50 °C to +300 °C and with a heating capacity of up to 3 kW. Excellent heating/cooling performance guarantees very short heat-up and cool-down times. Powerful pump With an extremely powerful pressure/suction pump with performance values up to 31 l/min or 0.92 bar (pressure) and -0.4 bar (suction), the MAGIO series offers the strongest pump in its class and is therefore perfectly suited for challenging external temperature tasks. To ensure maximum resistance against chemical substances, all wetted parts are made from stainless steel. Modern touch display The high resolution, modern TFT touch display has a multi-lingual user interface and shows all important information at a glance. Three large, predefined main screens clearly display data and graphics with various application priorities. All display functions are easy to operate with a fingertip. External temperature control MAGIO refrigerated circulators are perfect for external temperature tasks thanks to their powerful pumps and wide temperature range. Extensive accessories and excellent dynamics mean that the MAGIO circulators can be modularly and individually adapted to the most challenging applications. Simple data exchange Modern interfaces make easy remote control and practical data management possible as well as allowing integration into process structures. All MAGIO units come with integrated Pt100 connection, USB interface, RS232 and Ethernet. Analog interfaces are optionally available as accessories. Products MAGIO MS refrigerated / heating circulator with extremely powerful pressure/suction pump and intuitive touch display As with all circulators from the MAGIO range, the refrigerated circulators stand out thanks to their premium quality, high performance and intuitive operation. The devices offer extra strong pressure and suction pumps, thus fulfilling the highest demands for temperature control of external applications. Whether in basic research, material testing or technical systems – the MAGIO refrigerated circulators offer high-tech solutions for high customer requirements. MAGIO MS and MX bridge mounted circulators with extremely powerful pump and intuitive touch display MAGIO bridge mounted circulators combine high temperature control performance with maximum flexibility. The adjustable bridge means that the circulators can be used with bath tanks up to a filling volume of 100 liters. MAGIO MS / MX heating circulators with extremely powerful pumps, intuitive touchscreen displays Like all circulators in the MAGIO range, the heating circulators are characterised by premium quality and high performance combined with intuitive usability. The devices offer extra powerful pressure and suction pumps to meet the most challenging demands for temperature control of external applications. Samples can also be temperature controlled in the internal bath of the high-quality, insulated and closed bath tank.

MyGo

MyGo Pro

The MyGo Pro real-time PCR instrument provides unmatched performance in a convenient format. Novel Full Spectrum Optics deliver 120 optical channels of fluorescence data from every tube in parallel, with no moving parts, for reliable multiplex PCR. High performance Peltier elements, and solid silver blocks, provide both speed and world leading thermal uniformity. The result is rapid, precise, quantitative PCR and melting point analysis. Advanced algorithms combined with an intuitive user interface support a broad range of applications, operating systems and connection options. MyGo Mini The MyGo Mini is the world’s most compact real-time PCR instrument, with no moving parts for silent operation and maximum reliability. It provide users with great results over a broad range of applications.

TELEDYNE HANSON RESEARCH

VISION® G2 CLASSIC 6

The Vision G2 Classic 6 dissolution tester is the compact, rugged workhorse sibling to the Vision G2 Elite 8. Named in honor of the world’s first dissolution tester, a six-position test station introduced by Hanson Research in 1969, the G2 Classic 6 is precision engineered to ease the rigors of manual dissolution testing. The G2 Classic 6 meets and exceeds worldwide standards including compliance with USP, FDA, ASTM, EP, JP, CE, CSA, RoHS, and 21 CFR Part 11. FEATURES ▪ Award-winning design (2 across x 3 deep) provides easy access to all vessels ▪ Compact footprint saves valuable bench space ▪ 6-position Easi-LockTM vessel plate ensures proper vessel centering ▪ Up to 100 protocols stored (create, manage, call routines) ▪ Superior coating protects vessel plate from corrosion ▪ Fixed drive head guarantees repeatable, drive head positioning ▪ No tools or adjustments needed to switch among USP App. 1, 2, 5, 6, and 150 mL and 250 mL small volumes ▪ “Quick Test” feature begins tests immediately with the push of a button ▪ Adaptable for automated sampling

TELEDYNE HANSON RESEARCH

VISION® G2 ELITE 8

The Vision G2 Elite 8 dissolution tester is a versatile performance machine, built with the highest quality components and engineering. The G2 Elite 8’s ergonomic design and workhorse performance make it ideal for automation and extended applications as well as for 8-sample manual testing. The G2 Elite 8 meets and exceeds worldwide standards including compliance with USP, US FDA, ASTM, EP, JP, CE, CSA, RoHS, and 21 CFR Part 11. VISION G2 DISSOLUTION TESTING Vision G2 dissolution testers are designed with over 60 years of dissolution expertise and know-how. The modular design is plug-and-play ready making these systems upgradeable or automated without the need for separate firmware. They come standard with a full color touchscreen and intuitive menus, giving users the confidence of precision control for speeds 25-250 rpm and temperature 25-55 °C. Powerful programming, backed by a robust security system for 25 users, features the ability to create up to 100 unique protocols that can be conveniently transferred by flash drive to other Vision G2 testers, resulting in higher throughput and sample analysis.

TELEDYNE HANSON RESEARCH

CD14 COMPARATIVE DISSOLUTION

The Teledyne Hanson 14-vessel CD14 Comparative Dissolution Tester runs two methods simultaneously or independently—ideal for bioequivalence studies of generic vs. innovator drug formulations. The 14 stirring positions allow for 6+1 or 12+2 configurations for improved workload efficiency in R&D, formulations, QC, and stability-test labs. With digital temperature probes at 12 positions the CD14 comparative dissolution tester is able to test two different formulations with separate settings for every parameter under the same temperature conditions. FAST, POWERFUL COMPUTER CONTROL The CD14 is controlled by a fast, powerful computer built into the color touch screen display mounted to the drive head. The adjustable tilt angle accommodates operators of different heights while the Linux-based operating system with its own SQL database responds instantly to user input. The highly durable resistive touch screen works with gloves on or off. An easy-to-use interface includes context-sensitive help; logs for events, errors, test reports, test history, and service; rapid programming of new methods; ability to search database by any combination of fields; import/export including full system backup; programmable alarms for automatic power-on and warm-up; countdown to sampling points; tools including full system diagnostics; and more. CD14 FEATURES AND BENEFITS ▪ The CD14 provides the smallest footprint in the 14-vessel class: 85 cm W x 61 cm D. Precision vessel centering system exceeds the most demanding enhanced mechanical specifications. ▪ Store up to 500 protocols (methods) on-board. ▪ Run two different 6 vessel methods simultaneously or one 12-vessel method. ▪ Rugged water bath with low-position front port for ease of draining. ▪ Heater/circulator slides out for ease of servicing. ▪ Large color touch screen with adjustable tilt angle for operators of different heights. ▪ Compatible with Apparatus 1, 2, 5, and 6. ▪ Spindle speed: 25 rpm to 250 rpm, accurate to ± 1 rpm with displayed resolution 0.1 rpm. ▪ Temperature: programmable from 25.0 °C to 50.0 °C with accuracy of ± 0.5 °C. ▪ Digital temperature probes: 10 °C to 60 °C with accuracy of ± 0.1 °C from 30 °C to 55 °C, and displayed resolution of 0.01 °C. ▪ Compliant with USP, EP, JP, US FDA Enhanced Mechanical Calibration and ASTM E2503 standards. ▪ Seamless integration with CD AutoPlusTM autosamplers and AutoFillTM fraction collectors. 21 CFR PART 11 COMPLIANCE The CD14 onboard database stores up to 100 users with three levels of security (operators, managers, and administrators) with the ability to customize permissions and profiles at each level. The CD14 biometric fingerprint reader allows rapid enrollment of one or two fingers and provides positive ID of instrument operators. A password-only option is also included. Customize your own report formats and approval systems by specifying up to three signatures per report. An extensive audit trail records all system events and logs any changes made by users. System configurations are stored on-board and the system logs any changes to methods and configurations. SERIALIZED COMPONENTS All critical components of the CD14 are identified by unique serial numbers traceable to the factory level including the spin-shafts installed into the drive head, all baskets and paddles, and all dissolution vessels. The part number and serial number of each vessel are laser-engraved into the top of the vessel rim in large, easy-to-read type, such that breakage of the glass will not destroy identifying information. The on-board database of the CD14 stores the system configuration including the serial numbers of all vessels, paddles, and baskets, and the position into which each item is installed. PRECISION VESSEL CENTERING SYSTEM Each dissolution vessel installs into an adjustable bracket attached to the vessel plate. These vessel-centering brackets allow precision adjustments to the dissolution vessel’s position in relation to the spin-shaft and any apparatus attached to it. The system allows fast and easy vessel centering to meet or exceed USP and/or ASTM mechanical calibration specifications. CD AUTOPLUS AND AUTOFILL The CD AutoPlusTM autosampler is designed to work with the CD14 Comparative Dissolution tester. The CD AutoPlus comes with 6 sampling channels, and DissoScanTM or MaximizerTM configurations. Precision syringe pump mechanics, all-inert tubing and valves, and color touchscreen programming with up to 100 protocols are standard on each instrument. The AutoFillTM is a precision fraction collector fully compatible with all AutoPlus autosampler models.

TELEDYNE HANSON RESEARCH

PHOENIX DRY HEAT SYSTEMS

The new PhoenixTM dry heat diffusion testing systems from Teledyne Hanson Research provide manual and automated instruments that are more compact, easier to use, and more precise than conventional systems. The Phoenix family of products includes an advanced cell design, a six‐cell manual sampling system with a compact footprint, and an automated sampling system capable of testing up to 24 diffusion cells at once. The Phoenix DB-6 and Phoenix RDS systems and their components are protected under U.S. patent 10,753,841. PHOENIXTM DRY HEAT DIFFUSION CELLS The new PhoenixTM Dry Heat Diffusion Cell is designed for precision, versatility, and ease‐of‐use in diffusion‐testing labs. In manual sampling applications, the wide opening in the arm accommodates standard pipette tips. For maximum versatility, lab analysts can choose from small, medium, or large borosilicate glass cells and, using special volume‐adjustment mixer/inserts, can obtain receptor media volumes from 10 mL to 30 mL. An array of cell cap kits accommodates all 25 mm membranes, orifice diameters from 9 mm to 20 mm, and dosage volumes from 0.25 mL to 6.2 mL. A convenient fill mark on the sampling arm indicates the cell is filled. Phoenix cells are easily inserted and removed from the heating block. Cell preparation, including dosage application, bubble detection, and bubble removal, is fast and easy. PHOENIX DB‐6 MANUAL DIFFUSION SYSTEMS The Phoenix DB‐6 dry heat diffusion system provides a compact footprint for six‐cell testing. Precision heating and stirring systems contained within the block makes the system fully portable, able to be placed in any position the analyst chooses for faster, easier cell preparation. With precise control of mixing speeds from 200 rpm to 900 rpm, and temperatures from 25 °C to 40 °C, the system meets or exceeds USP <1724> specifications. An advanced color touch screen running on an embedded single‐board computer with a built‐in SQL database and real‐time clock provides advanced monitoring, diagnostic, and reporting capabilities, user‐friendly programming and navigation, storage for up to 100 test protocols, and configurable security for up to 50 users. The large, bright display allows key parameters to be seen from a distance, including speed, temperature, elapsed time, and time to next sample. When sampling is due, the system alerts the operator with the cell position, a countdown timer, and an audible beep. Test reports are delivered via the Teledyne Hanson serial validation printer. PHOENIX RDS AUTOMATED DIFFUSION TESTING The Phoenix RDS Robotic Diffusion Station refines the art of diffusion testing by incorporating Teledyne Hanson’s breakthroughs in four areas: diffusion cell design; heating and stirring; automated sampling and collection; and computerized control. The dry heat diffusion cell at the heart of the system delivers significantly improved test results as compared to traditional water‐jacketed, displacement‐sampling systems. The precision heating and stirring components built into each of the six‐cell blocks provide outstanding control of temperature and speed. Automatic sampling and collection are accomplished through a syringe driven probe on an XYZ platform controlled by Teledyne Hanson’s sophisticated Diffusion Master software. The automated system mimics the way sampling, collection, and media replace are performed by laboratory analysts when working manually, while simultaneously reducing the potential for variances due to procedural inconsistencies. The modular design of the six‐cell dry‐heat block allows laboratories to move smoothly between manual and automated methods when scaling to higher numbers of experiments. BUILD YOUR OWN PHOENIX DIFFUSION TESTING SYSTEM The Build Your Own System tool is an interactive way to explore the capabilities of Teledyne Hanson’s diffusion-cell-testing platform known as Phoenix Dry Heat Systems. The configurator will automatically guide you through the steps required to build your own diffusion cell testing system. It will ask you to choose between manual or automated sampling; various cell sizes and mixer-insert combinations to achieve specific receptor media volumes; choices of cell cap kits having different donor chamber volumes and membrane exposed areas (orifice diameters); and so on. It is recommended to first review the configurator instructions. If you have already reviewed the instructions, you can go directly to the “Build Your Own Phoenix Diffusion Testing System” configurator page.