SFC Prep 350 System

Waters’ suite of bulk-scale supercritical fluid chromatography (SFC) purification systems offers the optimal system for the amount of sample you need to purify. These systems easily allow you to purify a large amount of one sample. When faster and more cost-effective means sustainable business operations, SFC is the purification technique that makes the difference.

The preparative-scale SFC Prep 350 System is an automated system that features co-solvent gradient, high pressure separators for quantitative recovery of purified products, such as enantiomers, complex synthetic chemicals and natural products. The system is designed for chiral and achiral separations.


  • High pressure CO2 pump
  • High pressure co-solvent pump
  • Injection module
  • UV-Vis detector
  • Fraction collection module
  • Automated Back Pressure Regulator (ABPR)
  • ChromScope Software

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